Does vaping increase the likelihood of SARS-CoV-2 infection? Paradoxically yes and no
Rattapol Phandthong, Man‐Kin Wong, Ann Song, Teresa Martínez, Prue Talbot
2023American Journal of Physiology-Lung Cellular and Molecular Physiology13 citationsDOIOpen Access PDF
Abstract
Data on the relationship between electronic cigarettes (ECs) and SARS-CoV-2 infection are limited and contradictory. We investigated the impact of EC aerosols and their ingredients on SARS-CoV-2 infection of human bronchial epithelial cells. Our data show that specific ingredients in EC aerosols impact the susceptibility to SARS-CoV-2 infection. Propylene glycol (PG)/vegetable glycerin (VG) alone or PG/VG plus nicotine enhanced infection through different mechanisms, whereas benzoic acid in JUUL aerosols mitigated the increased infection caused by these ingredients.
Topics & Concepts
NicotineChemistryBiologyMedicineInternal medicineSmoking Behavior and CessationInhalation and Respiratory Drug DeliveryLong-Term Effects of COVID-19