Protein cross-linking in primary cultured mouse hepatocytes by dehydropyrrolizidine alkaloids: Structure–toxicity relationship
Fen Xiong, Kaiyuan Jiang, Yan Chen, Zhengcai Ju, Li Yang, Aizhen Xiong, Zhengtao Wang
Topics & Concepts
PyrrolizidineToxicityIn vivoCytotoxicityChemistryIn vitroBiochemistryCytochrome P450Acute toxicityEnzymePharmacologyStereochemistryBiologyGeneticsOrganic chemistryPlant Toxicity and Pharmacological PropertiesDrug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug Metabolism