Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms
Christian B. Billesbølle, Caleigh M. Azumaya, Rachael C. Kretsch, Alexander S. Powers, Shane Gonen, Simon Schneider, Tara Arvedson, Ron O. Dror, Yifan Cheng, Aashish Manglik
Topics & Concepts
HepcidinFerroportinChemistryInternalizationHemochromatosisBiophysicsCell biologyDMT1Iron homeostasisTransporterBiochemistryBiologyReceptorMetabolismInternal medicineInflammationMedicineImmunologyGeneIron Metabolism and DisordersHemoglobinopathies and Related DisordersPlant Micronutrient Interactions and Effects