Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells
Azubuike P. Ebokaiwe, Emmanuel Mfotie Njoya, Yuwen Sheng, Zhonghui Zhang, Sheng Li, Zongyuan Zhou, Zhe Qiang, Ting Peng, Ahmed A. Hussein, Guolin Zhang, Xiaoxia Lü, Lin Li, Fei Wang
Topics & Concepts
SalinomycinIndoleamine 2,3-dioxygenaseCancer researchTriptolideSTAT proteinJanus kinaseSTAT1Cell growthKynurenineChemistrySignal transductionBiologyApoptosisBiochemistrySTAT3TryptophanAntibioticsAmino acidTryptophan and brain disordersEpigenetics and DNA MethylationImmune cells in cancer