Astragaloside IV targets PRDX6, inhibits the activation of RAC subunit in NADPH oxidase 2 for oxidative damage
Chuanjing Cheng, Kaixin Liu, Fukui Shen, Jinling Zhang, Yang Xie, Suyun Li, Yuanyuan Hou, Gang Bai
Topics & Concepts
Oxidative stressChemistryMechanism of actionOxidative phosphorylationProtein subunitNADPH oxidaseSuperoxidePharmacologyBiochemistryCell biologyBiologyEnzymeIn vitroGeneTraditional Chinese Medicine AnalysisMedicinal Plants and Bioactive CompoundsNeutrophil, Myeloperoxidase and Oxidative Mechanisms