Litcius/Paper detail

Highly efficient conversion of cellulose and hemicellulose using an innovative ternary deep eutectic solvent: Achieving the green and complete use of lignocellulose

Jianxun Ma, Nyuk Ling, Wenqi Zhang, Jianfeng Zhang, Yue Ma, Guang Chen, Yang Sun, Jihong Wang, Chunyu Sun

2025Industrial Crops and Products12 citationsDOIOpen Access PDF

Abstract

Efficient pretreatment plays a key role in enhancing lignocellulose resources utilization. This study introduces a novel lignocellulose conversion approach using a newly developed ternary deep eutectic solvents (DES) consisting of Choline Chloride, Urea, and Ethylenediamine (ChCl-U-EDA 1:1.4:0.6). The enzymatic efficiencies of cellulase and hemicellulase reached 90.99 % and 76.77 %, respectively. Under the condition of 110 °C, 90 min, and a 1:15 solid to liquid ratio, the enzymatic hydrolysis of DES-pretreated lignocellulose yielded glucose and xylose at 0.52 g/g and 0.21 g/g, respectively. The lignin isolated from ChCl-U-EDA pretreatment displayed a more preserved structure with enhanced retention of β-O-4 bonds. Reduced density gradient analysis and molecular dynamics simulation indicated that the hydrogen bonding between lignin and ChCl-U-EDA facilitates the detachment of lignin from lignocellulose. The extracted lignin was then fabricated into a hydrogel for yeast immobilization, facilitating bioethanol production from glucose and xylose. After ten cycles, the average sugar to ethanol conversion was 0.448 g/g, corresponding to 89.6 % sugar conversion to ethanol. Reuse of ChCl-U-EDA resulted in 62.13 % lignin collection after 5 cycles. This study proposes a novel approach for the comprehensive and sustainable conversion of lignocellulose in an environmentally friendly and efficient manner. • I ChCl-U-EDA pretreatment detach lignin and remain more β-O-4 bonds. • II Cellulase and hemicellulase efficiency increase to 90.99 % and 76.77 %. • III Quantum chemical elaborates the mechanism of lignin detachment. • IV 89.6 % sugar converted into ethanol, sugar-ethanol conversion is 0.448 g/g

Topics & Concepts

HemicelluloseCelluloseDeep eutectic solventTernary operationEutectic systemChemistryChemical engineeringSolventPulp and paper industryMaterials scienceOrganic chemistryComputer scienceAlloyEngineeringProgramming languageCatalysis for Biomass ConversionAdvanced Cellulose Research StudiesLignin and Wood Chemistry