Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response
Lu Wang, Xiaohui Wang, Lina Kong, Shuyuan Wang, Kai Huang, Jingjing Wu, Changyuan Wang, Huijun Sun, Kexin Liu, Qiang Meng
Topics & Concepts
IsoliquiritigeninOxidative stressGCLCGCLMInflammationInflammasomePharmacologyApoptosisLiver injuryReactive oxygen speciesKEAP1ChemistryImmunologyBiologyBiochemistryDownregulation and upregulationTranscription factorGenePharmacological Effects of Natural CompoundsDrug-Induced Hepatotoxicity and ProtectionGinseng Biological Effects and Applications