Emergence of Novel Fluoroquinolone Resistance Mutations in <i>Mycoplasma bovis</i>, China, 2008–2023
Shimei Lan, Shuang Liu, Wenjing Cui, Zhangcheng Li, Huafang Hao, Ahmed Adel Baz, Jinjia Liang, Xiangrui Jin, Xinmin Yan, Pengcheng Gao, Fuying Zheng, Shengli Chen, Yuefeng Chu
Abstract
We investigated quinolone resistance in Mycoplasma bovis samples isolated in China during 2008-2023. Sequence type 52 was the dominant genotype; GyrA (S83F/Y) and ParC (S80R) protein double mutations caused high resistance to fluoroquinolones. Increased vigilance and surveillance of M. bovis infections in cattle will be needed to prevent disease.
Topics & Concepts
MicrobiologyAntibiotic resistanceBiologyDrug resistanceMycoplasmaVirologyAntibioticsMicrobial infections and disease researchToxoplasma gondii Research StudiesHerpesvirus Infections and Treatments