Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes
James Schiemer, Reto Horst, Yilin Meng, Justin I. Montgomery, Yingrong Xu, Xidong Feng, Kris A. Borzilleri, Daniel P. Uccello, Carolyn A. Leverett, Stephen Brown, Ye Che, Matthew F. Brown, Matthew M. Hayward, A. Gilbert, Mark C. Noe, Matthew F. Calabrese
Topics & Concepts
Ternary complexUbiquitin ligaseUbiquitinTernary operationChemistryCell biologyBruton's tyrosine kinaseBiochemistryComputational biologyBiologyBiophysicsTyrosine kinaseSignal transductionEnzymeComputer scienceGeneProgramming languageProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysChronic Lymphocytic Leukemia Research