Cucurbitacin IIb induces apoptosis and cell cycle arrest through regulating EGFR/MAPK pathway
Yuan Liang, Tiehua Zhang, Li Ren, Siyuan Jing, Zhuolin Li, Peng Zuo, Tiezhu Li, Yongjun Wang, Jie Zhang, Zhengyi Wei
Topics & Concepts
Epidermal growth factor receptorCell cycle checkpointApoptosisMAPK/ERK pathwayCell cycleCell biologyKinaseChemistryEGFR inhibitorsCancer researchTyrosine kinaseCell growthProtein kinase ASignal transductionBiologyBiochemistryReceptorAdvances in Cucurbitaceae ResearchToxin Mechanisms and ImmunotoxinsBioactive Compounds and Antitumor Agents