Pharmacological Characterization of the Novel and Selective α7 Nicotinic Acetylcholine Receptor–Positive Allosteric Modulator BNC375
Xiaohai Wang, Christopher J. A. Daley, Vanita Gakhar, Henry S. Lange, Joshua D. Vardigan, Michelle Pearson, Xiaoping Zhou, Lee Warren, Corin O. Miller, Michelle Belden, Andrew J. Harvey, Anton A. Grishin, Carolyn Coles, Susan O’Connor, Fiona Thomson, Joseph Duffy, Ian M. Bell, Jason M. Uslaner
Topics & Concepts
NeuroscienceAllosteric regulationAllosteric modulatorNicotinic agonistAcetylcholineAcetylcholine receptorNicotinic acetylcholine receptorDesensitization (medicine)Long-term potentiationPharmacologyMuscarinic acetylcholine receptorNeuroprotectionReceptorMedicinePsychologyChemistryInternal medicineNicotinic Acetylcholine Receptors StudyReceptor Mechanisms and SignalingCholinesterase and Neurodegenerative Diseases