Potential Antibacterial Action of α-Pinene
Mirla Fontes de Araújo Borges, Roosveni de Sousa Lacerda, Jásny Pintor de Assis Correia, Thamara Rodrigues de Melo, Sávio Benvindo Ferreira
Abstract
The indiscriminate use of antibiotics generates several problems for human health, the main one being bacterial resistance. The abuse of antibiotics is responsible for reducing the effectiveness of medicines, making it difficult to treat diseases and representing a major obstacle for researchers and health professionals. Natural alternatives have been widely studied, such as essential oils and their phyto-constituents, in order to verify their antibacterial action. This research aimed to identify the antibacterial activity of -pinene. This is a descriptive study, using a qualitative approach, with methodological experience based on an integrative review. The bibliographic survey was carried out in the LILACS and MEDLINE, though the Virtual Health Library, PubMed and Web of Science databases, using the following search strategies: Anti-bacterial agents AND -pinene for the PubMed and VHL databases, and (Antibacterial agents AND pinene) and (Antimicrobial AND -pinene) on the Web of Science. After reading the articles in full, 10 works were selected. -pinene was relatable, including its positive mix and its association with antimicrobials. The article points out that -pinene has wide potential in antimicrobial therapy in order to inhibit the growth of bacteria as an isolated result or as a synergist of antibiotics. However, they are bactericidal and bacteriostatic when against bacterial strains. Therefore, it is concluded that it is relevant to develop scientific research to analyze the effectiveness of this compound to the most diverse microorganisms that affect human health.