Genetic Code Expansion: A Brief History and Perspective
Mia Shandell, Zhongping Tan, Virginia W. Cornish
Abstract
translation systems to genetic encoding of UAAs in the native cell environment and whole organisms. We discuss innovative applications of the UAA technology to challenges in bioengineering and medicine.
Topics & Concepts
Genetic codeAminoacylationAmino acidComputational biologyTransfer RNATranslation (biology)MutagenesisFunction (biology)BiologyComputer scienceRNABiochemistryGeneticsMutationGeneMessenger RNARNA and protein synthesis mechanismsRNA modifications and cancerAdvanced biosensing and bioanalysis techniques