Newly Recognized CNS Tumors in the 2021 World Health Organization Classification: Imaging Overview with Histopathologic and Genetic Correlation
Ryan K. Rigsby, Pavan Brahmbhatt, Amit Desai, Girish Bathla, Blake A. Ebner, Vivek Gupta, Prasanna Vibhute, Amit Agarwal
Abstract
In 2021, the World Health Organization released an updated classification of CNS tumors. This update reflects the growing understanding of the importance of genetic alterations related to tumor pathogenesis, prognosis, and potential targeted treatments and introduces 22 newly recognized tumor types. Herein, we review these 22 newly recognized entities and emphasize their imaging appearance with correlation to histologic and genetic features.
Topics & Concepts
MedicinePathologyPathogenesisGlioma Diagnosis and TreatmentMeningioma and schwannoma managementBrain Metastases and Treatment