Genotoxicant exposure, activation of the aryl hydrocarbon receptor, and lipid peroxidation in cultured human alveolar type II A549 cells
Pavel Rössner, Helena Líbalová, Kristýna Vrbová, Tereza Červená, Andrea Rössnerová, Fatima Elzeinová, Alena Milcová, Zuzana Varchulová Nováková, Jan Topinka
Topics & Concepts
Aryl hydrocarbon receptorChemistryLipid peroxidationCYP1B1Arachidonic acidA549 cellBenzo(a)pyreneBiochemistryTranscription factorApoptosisCytochrome P450CarcinogenOxidative stressGeneEnzymeToxic Organic Pollutants ImpactCarcinogens and Genotoxicity AssessmentGlutathione Transferases and Polymorphisms